Study: Association between Obesity and Chronic Periodontitis

Chronic periodontitis is multi-factorial and numerous risk factors have been identified to contribute in the disease progression. This current study attempted to conduct a cross-sectional investigation in a population of patients with cardiovascular diseases in order to correlate the association between obesity [body mass index (BMI) and waist circumference (WC)] and periodontal disease parameters.

The study was of a cross-sectional design and a total of 201 patients were examined after obtaining their informed consent. Subjects who had a history of cardiovascular diseases and under treatment were included in the study. Two indicators of obesity were used: BMI and WC. The following periodontal parameters were assessed: Probing depth, clinical attachment level. The oral hygiene status of the subjects was assessed by the oral hygiene index (OHI). The influence of the BMI and other confounding variables on periodontitis severity was assessed using appropriate statistical analysis.

Significant association was seen with low density lipoproteins (LDL) and severity of periodontitis, triglyceride levels (TGL) and severity of periodontitis, cholesterol and severity of periodontitis, BMI and severity of periodontitis, OHI and severity of periodontitis. Significant association was seen with smoking and severity of periodontitis, BMI and severity of periodontitis, WC and severity of periodontitis, cholesterol and severity of periodontitis, OHI and severity of periodontitis.

The authors concluded that obesity has been implicated as a risk factor for several conditions including cardiovascular disease, diabetes, etc. In this study the relation between measures of overall and abdominal obesity (BMI and WC) and periodontal disease showed significant association. The authors concluded that obesity can act as a significant risk factor in progression of periodontitis.

Download our full newsletter here!

Lloyd E. Parmley, D.M.D. 
A Practice Limited to Periodontics • Implants • Gum Diseases
6909 Burlington Pike, Suite B • Florence, KY 41042-1618
859-371-6543 • 800-432-6543 • Fax 859-282-3112

Study: Periodontal Therapy in Chronic Periodontitis Lowers Gingival Crevicular Fluid Interleukin-1beta and DAS28 in Rheumatoid Arthritis Patients

By Bıyıkoğlu B, Buduneli N, et al.
Rheumatol Int. 2013 Jun 1

The purpose of this study was to evaluate clinical outcomes and effects of non-surgical periodontal therapy on serum, gingival crevicular fluid (GCF) interleukin-1beta (IL-1β) and tumor necrosis factor-alpha (TNF-α) levels in chronic periodontitis patients with/without rheumatoid arthritis (RA). Fifteen RA patients with chronic periodontitis (RA-P) and 15 systemically healthy non-RA chronic periodontitis patients (H-P) were recruited. Clinical periodontal recordings, GCF, and blood samples were obtained at baseline, 1, 3, and 6 months after periodontal treatment. GCF, serum IL-1β, TNF-α levels were analyzed by ELISA. Disease activity score 28 (DAS28) was used to assess RA clinical morbidity. Study groups were compared using
appropriate statistical analysis. Analysis was used to compare the data at baseline, 1, 3, and 6 months after periodontal therapy within the same group.

DAS28 decreased significantly after periodontal therapy in RA-P group. Serum TNF-α concentrations of H-P group were significantly higher than those of RA-P group, whereas IL-1β levels were similar. No significant change was observed in serum levels of these cytokines after periodontal therapy. GCF IL-1β amounts decreased significantly in both groups following treatment. At 6-months, H-P GCF IL-1β concentrations were significantly lower than baseline. DAS28 and GCF IL-1β correlated with clinical periodontal indices. Significant decreases in DAS28 and GCF IL-1β amounts after periodontal treatment suggest that periodontal therapy synergizes with systemic RA therapy to improve RA status.

Download the full newsletter here!

Lloyd E. Parmley, D.M.D. 
A Practice Limited to Periodontics • Implants • Gum Diseases
6909 Burlington Pike, Suite B • Florence, KY 41042-1618
859-371-6543 • 800-432-6543 • Fax 859-282-3112

Study: A 10-year Retrospective Clinical Evaluation of Immediately Loaded Tapered Maxillary Implants

The purpose of this study was to compare the effects of immediate loading (IL) and delayed loading (DL) on
peri-implant crestal bone loss around maxillary implants after long-term functioning. A retrospective chart review was conducted to assess the outcomes of 110 tapered, multithreaded implants placed for the treatment of one or more missing and/or unsalvageable teeth in the maxilla of 23 patients.

Implants were assigned to either the DL or IL database according to loading time. Marginal bone changes were calculated using standardized radiographs taken at implant placement (baseline) and during annual follow-ups. One implant failed in the DL group. After a mean followup of 111 months in the DL group and 119 months in the IL group, cumulative implant survival was 99.09% (DL =98.11%, IL = 100%). No observable bone loss was evident in 83.49% of the surviving implants. Cumulative success rates were 100% for the IL group and 98.11% for the DL group.

The authors concluded that immediately loaded maxillary implants showed long-term results comparable to delayed loaded maxillary implants.    

Download the full newsletter here!

Lloyd E. Parmley, D.M.D. 
A Practice Limited to Periodontics • Implants • Gum Diseases
6909 Burlington Pike, Suite B • Florence, KY 41042-1618
859-371-6543 • 800-432-6543 • Fax 859-282-3112